Vial Filling
At Its Best.

Between our Microcell Vial Filler and our SA25 Aseptic Filling Workcell, we’ve got your vial filling covered from drug development through commercialization. The design of our vial filling machines removes the need for human intervention leading to the isolator being completely closed and gloveless. A gloveless isolator reduces risk to the drug product and the robotics provide a consistently repeatable filling and closing process.


Benefits of Apera Vial Filling Machines

Accuracy and flexibility? Yes.

Both the Microcell ad SA25 can fill nested, pre-sterilized ISO vials from 2R to 50R. Changeover and decontamination between products can occur in as little as 15 minutes, allowing you to fill multiple sizes faster.

Vial filling is performed by our new Apera Dynamic Peristaltic Pump. The pump offers a 10x improvement in variability versus conventional peristaltic pumps. The pump’s accuracy level extends down to 0.1 mL — addressing a notable weakness of conventional peristaltic pumps losing accuracy at or below 1.0 mL. Users of the pump will be able to reduce overfill parameters and achieve higher batch yields.

I am part of an up and coming biopharma company

Reduced Risk / Speed to Market

While the Microcell is designed for drug development and early phase clinical trial production, the SA25 will carry you through late phase clinical trial production and commercial drug products.

I am part of a fully mature, mid-sized company
Operator working with a Apera SA25 Aseptic Filling Workcell, which can fill commercial and clinical drug products into vials, syringes and cartridges.

Nested Container

The Matrix Alliance was formed between primary packaging leaders in 2016, with the goal of collaboration between the members for compatibility and testing of nested containers (vials, syringes, cartridges) and closures (plungers, stoppers and caps). The Alliance verifies that Product Sets — the combination of a container and closure from different Matrix Alliance members — meet machinability and compatibility requirements when processed through Apera Aseptic Filling Workcells. Product Sets are commercially available products.

I am part of global company / major player